CJC-1295 ohne DAC 5mg

Eckdaten

• Substanz: CJC-1295 ohne DAC (Mod GRF 1-29)
• Größen: 5mg-Fläschchen
• Form: lyophilisiertes Pulver in einem versiegelten Glasfläschchen
• Reinheit: 99% (HPLC), unabhängig geprüft von Analiza Białek (Wrocław, Polen) – alle Laborberichte ansehen
• Lagerung: lyophilisiertes Pulver bei −20 °C zur Langzeitlagerung; 2–8 °C nach der Rekonstitution (siehe unseren Leitfaden zur Lagerung)
• Versand: aus den Niederlanden, mit Sendungsverfolgung, 1–4 Werktage innerhalb der EU (Versanddetails)
• Verwendung: nur für die Laborforschung – nicht zur Anwendung am Menschen oder Tier

Einleitung

CJC-1295 No DAC is a synthetic growth hormone-releasing hormone (GHRH) analog studied in laboratory research involving pituitary GH secretion, GHRH receptor pharmacology, and endocrine signaling dynamics. The absence of the Drug Affinity Complex (DAC) in this formulation creates a distinct pharmacological profile compared to its DAC-modified counterpart, making it a valuable tool for researchers investigating pulsatile growth hormone secretion patterns in controlled experimental models.

What Is CJC-1295 No DAC?

CJC-1295 No DAC is a modified synthetic peptide analog of GHRH, consisting of a 29-amino acid chain engineered without the DAC modification that would otherwise extend its half-life through albumin binding. In research settings, it is examined for its interaction with GHRH receptors on pituitary somatotroph cells and its role in stimulating pulsatile growth hormone release. Scientists study this compound to better understand pulsatile GH secretion dynamics and how different GHRH analog structures influence receptor binding and downstream signaling in laboratory models.

Struktur und Funktion

CJC-1295 No DAC is a 29-amino acid GHRH analog with structural modifications that enhance receptor binding affinity while maintaining a shorter half-life characteristic of native pulsatile GH secretion patterns. Its primary research function involves GHRH receptor binding and downstream cAMP-mediated GH secretion signaling in somatotroph cells. Researchers also investigate its pharmacokinetic profile and clearance patterns, making it relevant to studies in endocrine physiology, receptor pharmacology, and growth hormone axis regulation research.

Forschungsanwendungen

CJC-1295 No DAC is of interest across several areas of scientific investigation, including:

• Endocrine system investigation of pituitary receptor interactions and growth hormone pulse amplitude modulation in cellular and animal models
• Pharmacokinetic profiling examining clearance rates, metabolic pathways, and tissue distribution of the non-DAC peptide structure
• Receptor binding assay studies measuring binding affinity and selectivity at GHRH receptors for structure-activity relationship analysis
• Signal transduction research exploring cAMP-mediated pathway activation and downstream gene expression following receptor engagement
• Analytical method development using this compound as a reference standard for chromatography and mass spectrometry peptide detection validation

Forschungsresultate und wissenschaftliches Interesse

Studies have examined the role of CJC-1295 No DAC in GHRH receptor-mediated GH secretion, with findings supporting its ability to stimulate pulsatile hormone release in a pattern consistent with physiological GH dynamics in laboratory models. Research comparing its pharmacokinetic profile to DAC-modified variants continues to attract interest from the endocrinology and peptide pharmacology research communities. Its defined non-DAC structure provides a useful contrast compound for structure-activity relationship studies.

Qualität und Prüfung

Jede Charge wird von einem externen Labor unabhängig analysiert. Das Analysezertifikat für die aktuelle Charge ist auf dieser Seite veröffentlicht, sodass die Chargennummer auf der Ampulle direkt mit den Testergebnissen verglichen werden kann.

Verfügbarkeit und technische Daten

CJC-1295 No DAC is supplied as lyophilized powder in a 5mg vial, for use in controlled laboratory environments by qualified researchers. Shipped from the Netherlands with tracked delivery.

Dieses Produkt ist ausschließlich für Laborforschung bestimmt. Es ist nicht zur menschlichen Verzehr oder zur medizinischen, tierärztlichen oder therapeutischen Anwendung bestimmt.