SS-31 10mg

Key Facts

• Compound: SS-31
• Sizes: 10mg vial
• Form: lyophilized powder in a sealed glass vial
• Purity: 99% (HPLC), independently tested by Analiza Białek (Wrocław, Poland) – see all lab reports
• Storage: lyophilized powder at −20 °C for long-term storage; 2–8 °C after reconstitution (see our storage guide)
• Shipping: from the Netherlands, tracked, 1–4 business days within the EU (shipping details)
• Use: laboratory research only – not for human or veterinary use

Introduction

SS-31 (Szeto-Schiller 31, also known as MTP-131 or Bendavia) is a synthetic peptide studied in laboratory research involving mitochondrial function, oxidative stress modulation, and cellular bioenergetics. As a compound of significant scientific interest, SS-31 is used by researchers investigating fundamental mechanisms of mitochondrial dysfunction and reactive oxygen species management in preclinical model systems.

What Is SS-31?

SS-31 is a cell-permeable tetrapeptide designed to selectively accumulate in the inner mitochondrial membrane, where it interacts with cardiolipin — a phospholipid critical for membrane stability and mitochondrial function. In research settings, it is examined for its role in scavenging reactive oxygen species (ROS) and supporting mitochondrial bioenergetics. Scientists study this compound to better understand how targeted mitochondrial protection influences cellular survival and function under conditions of oxidative and metabolic stress.

Structure and Function

SS-31 is a tetrapeptide with an alternating aromatic-cationic structure that facilitates its concentration at the inner mitochondrial membrane. Its primary research function involves cardiolipin interaction, ROS scavenging, and restoration of mitochondrial membrane potential. Researchers also investigate its effects on ATP production and mitochondrial biogenesis, making it relevant to studies in cellular energetics, aging biology, and neurodegenerative disease research.

Research Applications

SS-31 is of interest across several areas of scientific investigation, including:

• Mitochondrial dysfunction investigation in neurodegenerative disorder models involving oxidative damage and protein aggregation
• Bioenergetic deficit studies in cardiovascular models, including heart failure and ischemia-reperfusion injury research
• Age-related metabolic decline exploration focusing on ATP production and ROS management in senescent cells
• Environmental toxin protection studies assessing mitochondrial stress responses in cellular assay systems
• Mitochondrial function rescue evaluation in genetic or induced disease models for therapeutic discovery research

Research Findings and Scientific Interest

Studies have examined the role of SS-31 in cardiolipin binding and mitochondrial membrane protection, with findings pointing to improved bioenergetic function and reduced oxidative stress markers in laboratory models. Research into its application across neurodegenerative, cardiovascular, and aging research continues to attract broad interest from the mitochondrial biology and cellular metabolism research communities. Its targeted mechanism supports precise investigation of mitochondrial pathways.

Quality and Testing

Every batch is independently analysed by a third-party laboratory. The certificate of analysis for the current batch is published on this page, allowing the batch number on the vial to be matched directly against its test results.

Availability and Specifications

SS-31 is supplied as lyophilized powder in a 10mg vial, for use in controlled laboratory environments by qualified researchers. Shipped from the Netherlands with tracked delivery.

This product is intended strictly for laboratory research purposes only. It is not intended for human consumption or for medical, veterinary, or therapeutic use.